avatar
smlu
Pathology

A 77-year-old man with a history of deep vein thrombosis, hypertension and remote splenectomy developed severe weakness and shortness of breath after a 6-day history of fever and chills. After his wife noted gurgling sounds, he was rushed to medical care but suffered a cardiac arrest en-route and died soon after arrival at the hospital. He died before he could be ventilated or started on therapy. A compete autopsy was performed. Post-mortem nasopharyngeal and lung swabs were positive for SARS-CoV-2. Figure 1: Diffuse alveolar damage. Figure 2: Hyaline membranes. Figure 3: Lymphocytic inflammatory infiltrate in the interstitium. Figure 4: Small blood vessel without thrombi or vasculitis. Figure 5: Diffuse alveolar damage, organizing stage. Note the thick interstitium. These images are from the lungs of one of the cases of the first reported complete autopsies in the English language literature, published online on April 10, 2020 in the American Journal of Clinical Pathology. Barton LM, Duval EJ, Stroberg E, Ghosh S, Mukhopadhyay S. Am J Clin Pathol 2020;153(6):725-733. PMID: 32275742